Trial of Routine Abdominal Wall Closure Versus Reinforcement With TIGR Matrix Onlay

Inclusion Criteria: * Reoperation * Age over 80 years * Generalised malignant decease (presence of distant metastases at the time of surgery) * COPD (Chronic obstructive pulmonary disease). Grade III-IV according to the GOLD classification (FEV1 \< 50% of the expected) * Serum Albumin level \<20 g/l * Sepsis. Infection in combination with two or more of the following: abnormal body temperature, heart rate, respiratory rate or blood gas, and white blood cell count. * BMI 35-45 (for patients with BMI\>45, no additional risk factors are required for inclusion) * Hemoglobin \<80 g/l * Diabetes with secondary complications (angiopathia, nephropathia or neuropathia) and insulin treatment * Steroid treatment (with at least 1 mg betamethasone daily or equivalent) for 7 days preoperatively * Smoking (at least 10 cigarettes a day for one year) * Chemotherapy (last administration within 2 weeks prior to surgery * Radiation therapy of the abdominal wall Exclusion Criteria: * Presence of mesh after previous surgery * Presence of incisional hernia * Wound length \<10 cm * Pregnancy * Age \< 18 years * Infected wounds