Avocado Fruit on Postprandial Markers of the Glycemic Response, Satiety/Appetite and Cardiometabo… (NCT02479048) | Clinical Trial Compass
CompletedNot Applicable
Avocado Fruit on Postprandial Markers of the Glycemic Response, Satiety/Appetite and Cardiometabolic Risk
United States29 participantsStarted 2015-06-01
Plain-language summary
The primary goal is to characterize the acute effects of avocado intake on glycemic and satiety/ appetite responses in relatively healthy overweight / obese adults. The secondary goal is to investigate risk factors for cardio-metabolic disease.
Who can participate
Age range25 Years – 60 Years
SexALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Men and women aged 25-60 yrs.
* BMI of 25 - 35 kg/m2
* No clinical evidence / history of cardiovascular, respiratory, renal, gastrointestinal, or hepatic disease
* Not taking over-the-counter or prescription medications / dietary supplements that may interfere with study procedures or endpoints (e.g., antioxidant supplements, anti-inflammatory, lipid-lowering or blood pressure lowering medications.
* Fasting blood glucose of 90-115 mg/dl
* Fasting insulin \< 13 U/L
* Non-smoker or past smoker (smoking cessation \> 2 yrs.)
* has at least 1 large, sturdy and well anchored vein in order to place a catheter
Exclusion Criteria:
* Aged \< 25 or \> 60 years
* BMI \< 25 kg/m2 or \> 35 kg/m2
* History of cardiovascular, respiratory, renal, gastrointestinal or hepatic disease
* Diabetes
* Uncontrolled blood pressure (\>140 / 90 mmHg)
* Have or had cancer other than non-melanoma skin cancer in past 5 years
* Taking over-the-counter or prescription medications or dietary supplements that may interfere with study procedures or endpoints (including protein powers, energy drinks)
* Fasting blood glucose \<90 or \> 115 mg/dl
* Fasting insulin ≥ 13 U/L
* Vegan dietary habits, unusual dietary habits or sensitive or allergic to any of the test meal components / ingredients
* Dislike avocados or non-consumers of avocados
* Current smoker
* Actively losing weight or trying to lose weight
* Drug or alcohol addiction
* Present with significant psychiatric or neurological di…
What they're measuring
1
Change in postprandial blood glucose concentration response for treatments compared to control over 6-hour postprandial period
Timeframe: Baseline to 6 hours
Trial details
NCT IDNCT02479048
SponsorClinical Nutrition Research Center, Illinois Institute of Technology