: Pharmacokinetics of Enoxaparin After Coronary Artery Bypass Graft Surgery

Inclusion Criteria: * BMI between 18-33 kg/m2 * Elective on-pump CABG operation * Indication for post-operative pharmacological thromboprophylaxis * Written informed consent obtained from the patient or his/her legal representative. Exclusion Criteria: * Other indications for anticoagulant therapy than thromboprophylaxis * Known heparin induced thrombocytopenia (HIT), or hypersensitivity to enoxaparin or heparin * Any long-term anticoagulant medication, expect low-dose aspirin * Major bleeding within the last week unless definitively treated * Blood platelet count \<20, P-TT \<20 % or INR \>1.7 * GFR less than 30 ml/min/1.73 m2 estimated from serum creatinine by applying Cockcroft-Gault equation 13 or chronic dialysis * Known HIV, HBV, or HCV infection * Pregnancy