Controlled Intermittent Alternate Occlusion (CIAO) Therapy for Intermittent Exotropia
Stopped: no fund
United States8 participantsStarted 2015-02-01
Plain-language summary
To determine the effectiveness of alternate occlusion therapy for the treatment of IXT among patients aged 3 to \< 11 years old.
Who can participate
Age range3 Years – 11 Years
SexALL
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Inclusion Criteria:
* Intermittent exotropia (manifest deviation) meeting all of the following criteria:
* Intermittent exotropia at distance OR constant exotropia at distance and either intermittent exotropia or exophoria at near
* Exodeviation at least 15PD at distance OR near measured by prism and alternate cover test (PACT)
* Exodeviation at least 10PD at distance measured by PACT
* No previous surgical or non-surgical treatment for IXT (other than refractive correction)
* Visual acuity in the worse eye 0.3 logMAR or better (20/40 on ATS HOTV or 70 letters on E-ETDRS) for children ≥ 3 years of age
* No interocular difference of visual acuity more than 0.2 logMAR (2 lines on ATS HOTV or 10 letters on E-ETDRS) for children ≥ 7 years of age
* Investigator not planning to initiate amblyopia treatment
* No hyperopia greater than +3.50 D spherical equivalent in either eye
* No myopia greater than -6.00 D spherical equivalent in either eye
* No prior strabismus, intraocular, or refractive surgery
* No abnormality of the cornea, lens, or central retina
* Investigator willing to observe the IXT untreated for 3 years unless specific criteria for deterioration are met.
Exclusion Criteria:
* N/A