Effect of Milk Formula Supplemented With L. Reuteri on Crying Time in Colicky Infants Less Than 3 Months Old

Inclusion Criteria: * Inclusion criteria : * less then 12 weeks of age * term infant (≥ 38 weeks gestational age) * birth weight \> 2,500g * infantile colic diagnosed according to modified Wessel's criteria, i.e. crying more than an average of 180 min/day during the 3 days prior to enrollment. * parental motivation to postpone changes in the infant feeding mode, unles Exclusion Criteria: * \- birth weight less than 2500 g * failure to thrive * chronic illness or major medical problem * gastrointestinal disease * cow's milk allergy ( confirmed prior to exclusion; difficult to diagnose so early ??) * use of any antibiotic or probiotic in the week (7 days) prior to enrollment * use of proton pump inhibitors in the week (7 days) prior to enrollment * if breastfeeding, use of probiotic by the mother in the week (7 days) prior to enrollment * infant receiving solid foods (such as cereals, mashed fruits or vegetable purée) * change of feeding mode planned by parents during the study period