Implantable venous access port infections are mainly due to coagulase negative staphylococci and may be managed by antibiotic lock therapy with retention of the port. Most of the time a vancomycin lock is used. Experimental data show that vancomycin may be poorly effective in eradicating the staphylococcal biofilm in the port. Another disadvantage of Vancomycin-containing lock solution is the occurrence of resistant organisms and the risk of catheter occlusion. Ethanol-containing lock solution is highly effective in vitro and does not expose to the risk of emergence resistance.
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Recovery at 12 week following the lock solution treatment completion
Timeframe: at 12 week
Favorable evolution without complication up to the end of implantable venous access port use
Timeframe: at 12 week
Favorable evolution without complication until the implantable venous access port withdrawal
Timeframe: at 12 week