An Open-Label, Multicenter Clinical Trial With Nivolumab (BMS-936558) Monotherapy in Subjects With Advanced or Metastatic Squamous Cell (Sq) Non-Small Cell Lung Cancer (NSCLC) Who Have Received at Least One Prior Systemic Regimen for the Treatment of Stage IIIb/IV SqNSCLC

For more information regarding BMS clinical trial participation, please visit www.BMSStudyConnect.com Inclusion Criteria: * ECOG Status: PS 0-1 \& PS 2 * Subjects with histologically or cytologically-documented SqNSCLC * Subjects must have experienced disease progression or recurrence during or after one prior platinum doublet-based chemotherapy regimen * Subjects must have evaluable disease by CT or MRI per RECIST 1.1 criteria * Subjects with treated or asymptomatic CNS metastases * Prior palliative radiotherapy must have been completed at least 14 days prior to study drug administration * Prior lines of antineoplastic therapy, including hemotherapy, hormonal therapy, immunotherapy, surgical resection of lesions, non-palliative radiation therapy, or standard or investigational agents for treatment of NSCLC, must be completed 28 days prior to the first dose of nivolumab * Males and Females, ages 18 or older Exclusion Criteria: * Subjects with untreated, symptomatic CNS metastases * Subjects with carcinomatous meningitis * Subjects with active, known or suspected autoimmune disease. * Subjects who received prior therapy with anti-PD-1, anti-PD-L1, anti-PD-L2, anti-CD137, or anti-CTLA-4 antibody (including ipilimumab or any other antibody or drug specifically targeting T-cell costimulation or checkpoint pathways) or who have previously taken part in a randomized BMS clinical trial for nivolumab or ipilimumab.