Drug Interaction Study Between AVP-923 and Itraconazole and Between AVP-786 and Itraconazole in Healthy Adult Subejcts

Inclusion Criteria: * Healthy adult males and females, 18 to 55 years of age * Body Mass Index (BMI) ≥19 and ≤30 kg/m2 (for both males and females) Exclusion Criteria: * History or presence of significant disease * History of substance abuse or dependence (except caffeine), or treatment for substance use disorder(s) within the year prior to screening or within 6 months for nicotine including e-cigarettes * Use of any tobacco-containing or nicotine-containing products within 6 months prior to the first dose * Use of any prescription or the over-the-counter medications within 14 days