Mesenchymal Stem Cell and Islet Co-transplantation

Inclusion Criteria: * Chronic pancreatitis patients who undergo TP-IAT. * \>18 years of age. * Patients with BMI from 18.5 to 30. * Renal function: \>90mls/min/1.73m squared * Normal INR/PT/PTT values for MUSC clinical laboratory standards * Diabetes free before surgery (fasting blood glucose\<125mg/dl). * No prior pancreatic surgery with the exception of transduodenal sphincteroplasty or Whipple/Beger procedure. * Patients with normal liver function as measured by serum levels of aminotransferase including alanine aminotransferase (ALT), and aspartate aminotransferase (AST), and total bilirubin levels. Exclusion Criteria: * Patients whose Hemoglobin, Hematocrit, and Platelet count are above or below normal values for MUSC clinical laboratory standards. * Patients who has hematological malignancy. * Patients who are under immunosuppression. * Patients with marked calcification disease on CT scan. * Patients with severe fibrosis and atrophy on pancreas MRI.