The Predictors of Successful Oral Dissolution Therapy in Radiolucent Renal Stones; A Prospective … (NCT02373384) | Clinical Trial Compass
CompletedPhase 4
The Predictors of Successful Oral Dissolution Therapy in Radiolucent Renal Stones; A Prospective Evaluation
Egypt182 participantsStarted 2015-02
Plain-language summary
The aim of the study is to evaluate the predictors of success of oral dissolution therapy in radiolucent renal stones in a large series of patients from a tertiary referral center in order to define the optimum case scenarios where oral dissolution therapy could be implemented.
Who can participate
Age range18 Years
SexALL
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Inclusion criteria
✓. Ability to give informed consent.
✓. Age more than 18 years.
✓. Absence of significant hydronephrosis, serious urinary tract infection, congenital anomalies or distal ureteric obstruction in the affected renal unit.
✓. Normal cardiac, hematological, and renal functions.
✓. Primary or recurrent renal stone.
✓. Patients with residual renal stones after primary intervention whether open surgery, endoscopic or ESWL.
✓. Peripheral calyceal stones or stone in the renal pelvis with no significant hydronephrosis.
✓. Stone size less than 3 cm in maximum diameter
Exclusion criteria
✕. Inability to give informed consent.
✕. Age less than 18 years
✕. Patients with unremitting pain or serious urinary tract infection.
✕. Presence of significant hydronephrosis, congenital anomalies or distal ureteric obstruction in the affected renal unit.
✕. Abnormal cardiac, hematological or renal functions.
✕. Obstructing stone in the renal pelvis with significant hydronephrosis.
What they're measuring
1
The primary endpoint of this study will be change in stone surface area after 3 months of the determined protocol
Timeframe: participants will be followed for the duration of medical treatment which is specified to be 3 months