A phase 2, randomized, vehicle-controlled, double-blind study to assess the efficacy, safety and pharmacodynamics (PD) of topically applied CLS003 in otherwise healthy patients with cutaneous warts.
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Change from baseline in morphological wart assessment
Timeframe: Days 14, 28, 42, 70, 98
Change from baseline in Wart size and morphology assessment by standardized clinical photography
Timeframe: Days 14, 28, 42, 70, 98
Change from baseline in HPV viral load assessment of target lesions by quantitative PCR
Timeframe: Days 14, 28, 42, 70, 98
Reduction in wart size
Timeframe: Days 14, 28, 42, 70, 98
Change in the HPV viral load
Timeframe: Days 14, 28, 42, 70, 98
Change from baseline in mean HPV viral load
Timeframe: Days 14, 28, 42, 70, 98
Percent clearance of warts
Timeframe: Days 14, 28, 42, 70, 98