Accumulating evidence suggests that repeatedly breathing low oxygen levels for brief periods (termed intermittent hypoxia) is a safe and effective treatment strategy to promote meaningful functional recovery in persons with chronic spinal cord injury (SCI). The goal of the study is to understand the mechanisms by which intermittent hypoxia enhances motor function and spinal plasticity (ability of the nervous system to strengthen neural pathways based on new experiences) following SCI.
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Change in overground walking endurance
Timeframe: Baseline, immediately after intervention (day 1 and day 5), and at follow-ups (one week and two weeks)
Change in muscle strength
Timeframe: Baseline, immediately after intervention (day 1 and day 5), and at follow-ups (one week and two weeks)