Prospective, multi-center, non-randomized, historical controlled, post-market study of patients requiring surgical repair of a focal articular cartilage lesion or osteochondral defect in the knee.
Who can participate
Age range18 Years
SexALL
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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Pre-procedure KOOS Pain subscale score less than or equal to 70.
* ICRS grade 3 or 4 focal articular cartilage lesion on the medial femoral condyle, lateral femoral condyle or trochlea, which measures less than or equal to15mm in diameter.
* Cartilage lesion is amenable to treatment with a single BioMatrix CRD or an osteochondral autograft.
Exclusion Criteria:
* Previous cartilage repair procedure (i.e., microfracture, OATS, ACI) at the intended implantation site.
* Clinically significant (\> 5 degrees) varus or valgus malalignment in either knee.
* Osteoarthritis in the injured knee.
* Inflammatory arthropathy
* Osteomyelitis or other active infection in either lower limb.
* Cortisone or hyaluronic acid knee injections in the past 3 months
* Body mass index greater than 35.