CompletedNot Applicable

Direct or Subacute Coronary Angiography in Out-of-hospital Cardiac Arrest

Denmark, Netherlands1,003 participantsStarted 2014-12

Plain-language summary

The overall aim of this prospective, randomized study is to investigate whether acute coronary angiography (within 120 minutes) with a predefined strategy for revascularization, will improve 30-day survival in patients with out of hospital cardiac arrest with no signs of ST-elevation on ECG after Restoration of Spontaneous Circulation (ROSC). The patients will be randomized to a strategy of immediate coronary angiography within 120 minutes or to a strategy of delayed angiography that may be performed three days after the cardiac arrest.

Who can participate

Age range18 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Witnessed out of hospital cardiac arrest * Restoration of Spontaneous Circulation (ROSC) \>20 minutes * Coronary angiography is expected to be performed within 120 minutes from inclusion and randomization at hospital Exclusion Criteria: * Patient age \<18 years * Obvious extracardiac genesis of cardiac arrest such as trauma, hemorrhagic shock, and / or asphyxia (eg drowning, suffocation, hanging, exposure to fire smoke) * Terminally ill patients with a life expectancy of less than 1 year * Patients with ST-elevation * Known pregnancy * Patient awake GCS \>8 (Glasgow Coma Scale)

What they're measuring

30 day survival

Timeframe: 30 days

Trial details

NCT IDNCT02309151

SponsorUppsala University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2026-04

View on ClinicalTrials.gov More Out-of-Hospital Cardiac Arrest trials