Study of Tedizolid Phosphate in Adolescents With Complicated Skin and Soft Tissue Infection (cSSTI) (MK-1986-012)

Inclusion Criteria: * Males or females 12 years to \<18 years * Adequate venous access for IV administration of study drug for at least 24 hours (for participants receiving IV medication) and collection of protocol-specified blood samples * Local symptoms must have started within 7 days before Study Day -1 * cSSTI meeting at least 1 of the clinical syndrome definitions. * Suspected or documented Gram-positive infection from baseline Gram stain or culture. * Parent/legally authorized representative (LAR) able to give informed consent and willing and able to comply with all required study procedures. Assent is also required of children who in the Investigator's judgment are capable of understanding the nature of the study Exclusion Criteria: * Uncomplicated minor skin and skin structure infections such as pustules, folliculitis, furuncles, minor abscesses (small volume of suppuration not surrounded by cellulitis/erysipelas), impetiginous lesions, superficial or limited cellulitis/erysipelas, and minor wound associated foreign body reactions (eg, stitch abscesses) * Known bacteremia, severe sepsis or septic shock * Recent history of opportunistic infections where the underlying cause of these infections is still active (eg, leukemia, transplant, acquired immunodeficiency syndrome) * Hypersensitivity to tedizolid phosphate or any component in the formulation * Hypersensitivity to all of the comparator drugs; hypersensitivity to a comparator drug does not preclude participation…