CompletedPhase 4

Trial of IV NTG for CD After Second Stage Arrest for the Prevention of Uterine Extension

United States18 participantsStarted 2015-10

Plain-language summary

Randomized controlled clinical trial of IV nitroglycerin at cesarean delivery for second stage arrest of descent to prevent or uterine extension at the hysterectomy site.

Who can participate

Age range18 Years – 60 Years

SexFEMALE

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: women 37weeks or greater gestation diagnosed with second stage arrest of descent undergoing cesarean delivery - Exclusion Criteria: elective, active phase arrest cesarean delivery, successful operative vaginal delivery \-

What they're measuring

Number of Participants With Uterine Extension of Hysterotomy

Timeframe: During cesarean delivery, estimated to be within 4 hours after diagnosis of second stage arrest

Umbilical Artery Blood pH

Timeframe: At time of cesarean delivery, estimated to be within 4 hours after diagnosis of second stage arrest

Number of Participants With Deliveries After Which Neonate is Admitted to NICU

Timeframe: After cesarean delivery, estimated to be within 4 hours after diagnosis of second stage arrest

Number of Participants With Deliveries in Which Cord Blood Base Deficit is More Negative Than or Equal to Negative 12

Timeframe: At time of cesarean delivery, estimated to be within 4 hours after diagnosis of second stage arrest

APGAR at 5 Minutes

Timeframe: Immediately after cesarean delivery, estimated to be within 4 hours after diagnosis of second stage arrest

Trial details

NCT IDNCT02265965

SponsorUniversity of California, San Francisco

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2018-07-01

Results submitted2020-04-14

View on ClinicalTrials.gov More Prolonged Second Stage of Labor trials