Safety and Efficacy Assessment of Autologous Bone-marrow Derived Adult Mesenchymal Stem Cell Ther… (NCT02210624) | Clinical Trial Compass
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Safety and Efficacy Assessment of Autologous Bone-marrow Derived Adult Mesenchymal Stem Cell Therapy in Patients With Anoxic(or Hypoxic) Brain Injury Pilot Trial
South Korea4 participantsStarted 2013-03
Plain-language summary
The purpose of study is to evaluate the safety and efficacy of autologous bone marrow-derived stem cells therapy in patients with anaerobic (hypoxic) brain injury. Stem cell therapy is an emerging alternative treatment modality in incurable and intractable neurological disorders. This pilot study aims to evaluate the feasibility and safety of stem cells in anaerobic brain injury.
Who can participate
Age range18 Years – 75 Years
SexALL
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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Patients older than 14 days after the index event occurs in an oxygen-free brain injury patients
* Severe disability or moderate due to anoxic brain injury
* 18 years to 75 years
* Patients was 7 points less than Glasgow coma scale (GCS) After the resumption of blood flow circulation.
* anaerobic unexpected (hypoxic) cerebral ischemia Encephalopathy (It should not be a hypoxic brain ischemia was induced due to heart surgery, which is scheduled)
* Subjects agreed in writing that it will be participating in clinical research, as viewed from the legal representative (patient)
Exclusion Criteria:
* Patients who require ventilator continued
* Patients who had extracorporeal membrane oxygenation(ECMO) index event occurs at the time
* Patients who had a history of cardiac arrest prior to the occurrence of Index event
* End-stage people of less than 12 months is expected (incurable) disease patients
* Patients with cardiac arrest occurred due to brain trauma severe
* Patients with damage to other organs of severe
* Patients with bleeding or malignant current
* Pregnant patient
* Patients with central nervous system tumors undergoing radiation therapy or chemotherapy
* If the patient or are participating in other clinical trials, you are planning to participate, or patients three months after the end is not passed to participate in other clinical trials