Brain-Behavior Interactions in Tic Suppression (NCT02205918) | Clinical Trial Compass
CompletedNot Applicable
Brain-Behavior Interactions in Tic Suppression
United States30 participantsStarted 2017-07-01
Plain-language summary
The purpose of this study is to examine how the brain and environment interact to influence children's ability to suppress tics using a medical technology called Transcranial Magnetic Stimulation (TMS).
Who can participate
Age range12 Years – 18 Years
SexALL
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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Presence of motor and/or vocal tics for at least one year
* English fluency
Exclusion Criteria:
* Participants with medical conditions that are contraindicated for TMS (history of any known intracranial pathology, epilepsy or seizures, traumatic brain injury, brain tumor, stroke, implanted medical devices, current pregnancy or girls of childbearing age not using effective contraception, or any other serious medical conditions
* Left-handedness
* Previous diagnosis of psychosis, autism spectrum disorder, mental retardation, or cognitive disability
* Inability to undergo MRI
* Substance abuse or dependence within the past year
* History of ≥3 sessions of Habit Reversal Therapy or other treatment primarily comprised of tic suppression strategies
* Current suicidal intent
* Current neuroleptic medications, as these medications are known to lower seizure threshold