Cyclic Exclusive Enteral Nutrition as Maintenance Therapy for Pediatric Crohn's Disease

Inclusion Criteria: * 6-18 years * Confirmed Crohn's disease (L1, L2, L3+/- L4a/b) * new-onset disease or acute relapse treated with enteral nutrition * responding to induction therapy with exclusive enteral nutrition with complete clinical remission at inclusion visit (wPCDAI\<12.5) * completed cycle of induction therapy of at least 6 weeks (6-12 weeks) * biological treatment by Remicade has to be stopped at least 8 weeks prior to inclusion * "wash out" of corticosteroids, immunosuppressors and treatment by Humira of minimally 4 weeks prior to inclusion * 5-ASA and derivates have to be stopped at least at screening visit * Antibiotics must be stopped at least 2 weeks prior to inclusion * Informed and signed consent Exclusion Criteria: * Patients with B2 or B3 disease behavior (intestinal/colonic stenosis (including ileo-caecal valve), intrabdominal abscess, fistulizing disease) * Patients not in remission on induction therapy (wPCDAI\>12.5) * Patients with isolated and severe perianal disease * Patients requiring surgical therapy at inclusion * Ongoing steroid medication * Ongoing immunosuppressor or biologics therapy * No informed consent * Currently participating or having participated in another interventional clinical trial during the last 4 weeks prior to the beginning of this study