Chronic Effects of Natural and Interesterified Fats Margarine on Insulin Sensitivity and Selected… (NCT02192047) | Clinical Trial Compass
CompletedNot Applicable
Chronic Effects of Natural and Interesterified Fats Margarine on Insulin Sensitivity and Selected Markers of Cardiovascular Diseases (CVD)
Malaysia85 participantsStarted 2012-09
Plain-language summary
The investigators hypothesized that there will be a significant difference between the effects of trans-free palm-, interesterified palm- and interesterified soybean oil blend on cardiovascular disease, inflammation, insulin resistance and obesity.
Who can participate
Age range20 Years – 60 Years
SexALL
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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Adult males and females, aged 20-60 yr
* Staff and students of International Medical University, IMU/ Staff of Malaysian Palm Oil Board, MPOB to facilitate centralized consumption of the test fats/snacks
* BMI 21 - 30 kg/m2
Exclusion Criteria:
* Abnomal liver function test (elevated transaminases- alanine aminotransferase,ALT; aspartate aminotransferase,AST))/ abnormal kidney function test (elevated plasma creatinine)
* History of type 2 diabetes mellitus, cancer, stomach ulcers, drug abuse or alcoholism
* Smokers
* On lipid/blood pressure- lowering medication/supplements
* Blood pressure\>140/90 mmHg
* Fasting total cholesterol \> 6.5 mmol/L
* Fasting TAG \> 2.0 mmol/L
* Candidates who are going abroad during the planned schedule for the dietary intervention