Klimadynon® in Comparison to Conjugated Oestrogens in Women Suffering From Menopausal Complaints

Inclusion Criteria: * Only postmenopausal (amenorrhea for 6 months at least) women may be enrolled in the study * Women after ovariectomy may also be enrolled if surgery was carried out at least 6 months prior to the enrollment. Only women between the age of 40 and 60 may be included * 2 weeks (control -1, week -2, day -14) before the beginning of the treatment the following hormone values must have been analyzed: * estradiol-17ß ≤ 0.15 nmol/l corresponding to ≤ 40 pg/ml and follicle stimulating hormone (FSH) ≥ 25 milliunits per milliliter (mU/ml) * These hormone analyses must be carried out at the competent local laboratory * In addition to other menopausal complaints the women must have hot flushes / outbreaks of sweating: * Diary: During the "run-in period" daily ≥ 3 hot flushes / outbreaks of sweating * Modified Menopause Rating Scale, 1st item twofold (week -2 and 0) ≥ 0.3 * A sum score taken twice from the modified (only items 1 - 6) Menopause Rating Scale within 2 weeks (week - 1 and 0) before the beginning of treatment must be ≥ 1.7 * In case of a pretreatment with estrogen a wash-out phase of 6 weeks is necessary in case of oral or transdermal administration. After the 4th week of wash-out the patient may be included in the "run-in period" Exclusion Criteria: * General criteria for exclusion: * Non-responder (= no therapeutic success) under a pretreatment with estrogen * Amenorrhea for \< 6 months * In case of an estrogen pretreatment last menstru…