UnknownNot Applicable

Effect of Magnesium Supplementation on Polycystic Ovary Syndrome

Iran70 participantsStarted 2014-06

Plain-language summary

This is a double-blind randomized clinical trial which will start at June 2014 and end on June 2015 in Isfahan city. Serum insulin level is considered as a key variable and the sample size calculated 70 persons (35 persons for control group and 35 persons for patient group). Patient group will receive magnesium supplement (250 milligram) and the other group will receive placebo which is similar to the magnesium tablets in color, odor and appearance both for 8 weeks. All subjects will complete 4 physical activity and 4 dietary records. Outcome measurements including sex hormone levels, metabolic and inflammatory profiles will be measured at the beginning and end of the study as well as anthropetric measurements.

Who can participate

Age range

20 Years – 45 Years

Sex

FEMALE

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Having PCOS according to the Rotterdam criteria, * Age between 20-45 years, * Lack of pregnancy and lactation, * Not having certain regime during last 3 months, * Non-smoking, * Not having diseases, including: diabetes, cardiovascular , hepatic, renal and thyroid, * Not taking supplements, * Being overweight (Kg / m 25 ≤ BMI) Exclusion Criteria: * Hormone Therapy, * Pregnancy and lactation during the study, * Severe weight loss (more than 2.5 kg per month) during the study

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Serum insulin level

Timeframe: 8 Weeks

Trial details

NCT IDNCT02178150

SponsorIsfahan University of Medical Sciences

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2015-10

Contact for this trial

Ahmad Esmaeilzadeh, Professor

3117922776 esmaillzadeh@hlth.mui.ac.ir

View on ClinicalTrials.gov More Polycystic Ovary Syndrome trials