TerminatedPhase 1/2

Safety and Preliminary Efficacy Study of V404 PDS in Uveitis

Stopped: Study terminated due to unacceptable frequency of drug related adverse events

United States7 participantsStarted 2014-04

Plain-language summary

This study is intended to evaluate the safety of V404 PDS in patients with chronic non-infectious uveitis. Secondarily, the study will evaluate whether V404 PDS can provide clinically measurable benefit over an extended period of time in patients with chronic non-infectious uveitis.

Who can participate

Age range18 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * 18 years of age or older * Confirmed diagnosis of active uveitis * Sufficient lens/media clarity * Meet best-corrected visual acuity criteria * Willing and able to use contraception Exclusion Criteria: * Pregnant, breast feeding * Uncontrolled glaucoma * Intraocular surgery or periocular/intraocular injections within 6 weeks * Periocular or intraocular steroid within 3 months * Prior vitrectomy * Prior corneal transplant * Prior fluocinolone implant * Allergy or sensitivity to study drug * Participation in other trial within 30 days * Abnormal liver function * History of positive serum tuberculosis test

What they're measuring

Frequency of adverse events

Timeframe: 6 months

Trial details

NCT IDNCT02125266

SponsorForsight Vision4

Sponsor typeINDUSTRY

Study typeINTERVENTIONAL

Primary completion2014-10

View on ClinicalTrials.gov More Uveitis, Posterior trials