Developing Rectal USPE Measures

Inclusion Criteria: * All participants must meet all of the inclusion criteria to participate in this study. * Eligible male participants must be 18 years of age or older * Eligible female participants must be 18-45 years of age Inclusion criteria include men and women who: * Report receptive anal intercourse (RAI) at least twice in the past 6 months, * Are willing to use each study product in conjunction with RAI on at least one occasion in each data collection period (resulting in a minimum of 3 RAI events during each product evaluation period; on average every 2 weeks, all 3 products across an average of 6 -12 weeks)) * Are willing and able to respond to study data collection systems via phone and internet, attend all study visits, and participate in in-depth qualitative interviews Exclusion Criteria: * Male and female participants will be ineligible if they: * Have a sensitivity or allergy to vaginal, anal, or rectal products, * Have a sensitivity or allergy to any of the ingredients contained in the study products, * Are HIV positive at baseline, or have a known HIV-positive sexual partner, * Have an active rectal or reproductive tract infection requiring treatment per current Centers for Disease Control (CDC) guidelines or symptomatic urinary tract infection (UTI). Infections requiring treatment include Chlamydia (CT)\*, gonorrhea (GC)\*, syphilis, active herpes simplex virus (HSV) lesions (note: HSV seropositivity with no active genital lesions is no…