CompletedNot Applicable

Effect of Genetic Variants on Fat-soluble Vitamin Bioavailability

France45 participantsStarted 2009-01

Plain-language summary

The aim was to identify minor genetic variations (single nucleotide polymorphisms) that explain the interindividual variability in bioavailability of fat soluble micronutrients (fat soluble vitamins and carotenoids).

Who can participate

Age range18 Years – 60 Years

SexMALE

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: gender : male age : 18 to 60 years old BMI: \[18 to 29.9\] kg/m2 Fasting Cholesterol concentration : \< 2,5 g/l Fasting triglyceride concentration \< 2 g/l Fasting glycemia ≤ 1,1 g/l Fasting Hemoglobin \< 13 g/dl HIV as well as hepatitis C and B negative Exclusion Criteria: smokers regular consumption of vitamin supplement \> 140 g/week alcohol vegetarian diseases drugs assumed to affect the metabolism of lipids or fat soluble micronutrients (e.g. ezetimibe)

What they're measuring

micronutrient concentration in plasma chylomicrons

Timeframe: 8 hours

Trial details

NCT IDNCT02100774

SponsorInstitut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2010-07

View on ClinicalTrials.gov More Biological Availability of Vitamins and Micronutrients trials