Methylphenidate ER Liquid Formulation in Adults With ASD and ADHD

Inclusion Criteria * Male or female participants between 18 and 40 years of age (inclusive) * Fulfills DSM-5 diagnostic criteria for autism spectrum disorder as established by the clinical diagnostic interview and ADOS * Fulfills DSM-5 diagnostic criteria for ADHD as established by the clinical diagnostic interview and confirmed by the K-SADS-E ADHD module * Participants with at least moderately severe symptoms of ASD as demonstrated by SRS raw score ≥ 85 and CGI-ASD severity score ≥ 4 * Participants with at least moderately severe symptoms of ADHD as assessed by AISRS score ≥ 24 and CGI-ADHD severity score ≥ 4 * Participants and/or their legal representative must understand the nature of the study. Participants and/or their legal representative must sign an IRB-approved informed consent form before initiation of any study procedures. * Participants and/or their legal representative must have a level of understanding sufficient to communicate with the investigator and study coordinator, and to cooperate with all tests and examinations required by the protocol. * Participant must be able to participate in mandatory blood draws. * Participant with major mood and/or anxiety disorders will be allowed to participate in the study provided they do not meet any exclusionary criteria. Exclusion Criteria * Impaired intellectual capacity (IQ \<85) * Participant is unable to communicate due to delay in, or total lack of, spoken language development (grossly impaired language skills) *…