Celecoxib in Decreasing the Damaging Effects of Sunburn in Healthy Volunteers

Inclusion Criteria: * The subject has Fitzpatrick skin type I, II, or III * If the subject is female and of childbearing potential (women are considered not of childbearing potential if they are at least 2 years post-menopausal and/or surgically sterile): * Has been using adequate contraception (e.g., condom, intrauterine device \[IUD\], diaphragm and spermicide gel combination) since her last menses and will use adequate contraception during the study, and * Is not lactating, and * Will begin taking study drug beginning 2 days after onset of menses * The subject is willing to abstain from the use of other non-steroidal anti-inflammatory drugs (NSAIDs) for the duration of the study * The subject is willing to abstain from the use of all topical agents applied to the buttocks for the duration of the study with the exception of lotion * The subject is willing to participate for the duration of the study * The subject has provided written informed consent prior to administration of any study related procedures Exclusion Criteria: * The subject is currently taking any medication that may alter the sunlight response or cause an adverse reaction * The subject has a history of melanoma, lupus, psoriasis, rosacea, porphyria, photosensitivity disorder, connective tissue disorder, or any disease that would increase the risk associated with study participation * The study has excessive hair, blemishes, nevi, uneven pigmentation, sunburn or suntan on the buttocks * The subject …