Purified CD34+ Cells Versus Peripheral Blood Mononuclear Cells in Treatment of Critical Limb Ischemia

Inclusion Criteria: * Rutherford scale of 4-5 * thromboangiitis obliterans, peripheral arterial disease, or arteritis caused by other etiologies, such as collagen diseases * surgical or endovascular procedures are considered unlikely to have successful long-term revascularization, or have failed * more than 4 weeks of critical limb ischemia * if present, a non-healing ulcer after more than 4 weeks of optimal care by a wound care physician and a nurse Exclusion Criteria: * within 3 months of an acute myocardial infarction * any contraindication for the administration of granulocyte colony stimulating factor (G-CSF)