Prophylactic Salpingectomy for the Prevention of the Ovarian Cancer: Comparison Between Surgical Techniques

Inclusion Criteria: * Patients subjected to a laparoscopic surgery for a benign gynecologic disease or who require tubal surgical sterilization, once they have accomplished their reproductive desire, and after the acquisition of a written consent for prophylactic salpingectomy and the ovarian preservation. * Age between 35 and 50 years * Regular menstruation with intervals between 22 and 35 days Exclusion Criteria: * Patients with a family history of ovarian cancer and with a known mutation of the BRCA1/2 genes * Patients with a current or a past history of cancer * Patients who don't consent to the prophylactic salpingectomy * Patients subjected to hysterectomy * Previous adnexal surgery * PCOS * Estrogen-progestin therapy in the 2 months prior to the enrollment * Acute or chronic pelvic inflammatory disorders * Malignant gynecological neoplasms * Prior chemotherapy or radiotherapy * Autoimmune diseases, chronic, metabolic, endocrine and systemic disorders, including hyperandrogenism, hyperprolactinemia, diabetes mellitus and thyroid disease * Hypogonadotropic hypogonadism * Taking medications that can cause menstrual irregularities * Other clinical conditions