Ovarian Reserve Modification After Lps Hysterectomy With Bilateral Salpingectomy (NCT02086344) | Clinical Trial Compass
UnknownNot Applicable
Ovarian Reserve Modification After Lps Hysterectomy With Bilateral Salpingectomy
Italy167 participantsStarted 2014-02
Plain-language summary
The aim of this RCT of study is to compare the standard TLH with adnexal preservation with TLH plus prophylactic bilateral salpingectomy (PBS) in terms of ovarian reserve and surgical outcomes
Who can participate
Age range35 Years – 50 Years
SexFEMALE
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Inclusion Criteria:
* Indication to laparoscopic hysterectomy
* Accomplished reproductive desire
Exclusion Criteria:
* Patients with a family history of ovarian cancer and with a known mutation of the BRCA1/2 genes
* Patients with a current or a past history of cancer
* Patients who don't consent to the prophylactic salpingectomy
* Previous adnexal surgery
* PCOS
* Estrogen-progestin therapy in the 2 months prior to the enrollment
* Acute or chronic pelvic inflammatory disorders
* Malignant gynecological neoplasms
* Prior chemotherapy or radiotherapy
* Autoimmune diseases, chronic, metabolic, endocrine and systemic disorders, including hyperandrogenism, hyperprolactinemia, diabetes mellitus and thyroid disease
* Hypogonadotropic hypogonadism
* Taking medications that can cause menstrual irregularities
* Other clinical conditions