3-Tesla MRI Response to TACE in HCC (Liver Cancer)

Inclusion Criteria: * Subjects must have signed an institutional review board (IRB)-approved informed consent document * Subjects must have verified unresectable hepatocellular carcinoma (HCC), diagnosed on the basis of clinical and imaging criteria * Subjects must be classified as TNM stage I, II, or III; alternatively, subjects may be classified as Barcelona Clinic Liver Cancer (BCLC) stage A or B * Subjects must be scheduled to undergo transarterial chemoembolization (TACE) * Subjects must have at least 1 lesion being targeted by TACE that is \> 2 cm in the longest cross-sectional (axial plane) diameter * Subjects must satisfy one of the following conditions pertaining to their eligibility to undergo orthotopic liver transplantation (OLT): * HCC that is within Milan Criteria, i.e., TACE is indicated as a "bridge" to OLT (Group I); or * HCC that is outside Milan Criteria, i.e., TACE is indicated as a means of "down-staging" into transplant eligibility (Group II) Exclusion Criteria: * Subjects who have received prior treatment for HCC (prior surgical procedures not related to HCC are allowed) * Subjects who have undergone prior radioembolization * Subjects with a central venous line * Subjects who have any type of biomedical implant, device and/or ferromagnetic material that can be displaced, perturbed, or otherwise malfunction due to mechanical, electronic, or magnetic means; these items may include: * Metallic fragments or shrapnel (such as from war wounds) * …