chronOS Inject in Proximal Tibial Fractures

Inclusion Criteria: * Subjects with closed proximal tibial fractures defined by : Tibia plateau, Schatzker I - VI, AO-OTA 41, AO-OTA 42 with bone defect * Skeletally mature adult 18 years or older, with close of growth plate at the time of surgery * Psychosocially, mentally and physically able to fully comply with this protocol including adhering to scheduled visits, treatment plan, completing forms, and other study procedures * Personally signed and dated informed consent document prior to any study-related procedures indicating that the patient has been informed of all pertinent aspects of the study Exclusion Criteria: * Open fractures with severe soft tissue damage * Proximal tibial fractures with tumor or osteomyelitis * Any tibial anatomy or disease process that would interfere with deployment or performance of the device as defined by the surgeon * Osteopenia or Osteoporosis: if dual energy x-ray absorptiometry (DEXA) is required, exclusion will be defined as a DEXA bone density measured T score \<=-1.0 * Known history of Paget's disease, osteomalacia, or any other metabolic bone disease * Morbid obesity defined as a body mass index \>40 kg/m2 or weight more than 50 kg over ideal body weight * Active malignancy. A patient with a history of any invasive malignancy (except non-melanoma skin cancer), unless treated with curative intent and there has been no clinical signs or symptoms of the malignancy \>5 years * Known or documented history of communicable disease, incl…