Ticagrelor vs Clopidogrel in Non-ST Elevation Acute Coronary Syndrome Patients Undergoing PCI With Bivalirudin.

Inclusion Criteria: * Hospitalised for chest pain and potential acute coronary syndrome. * Onset of the most recent cardiac ischemic symptoms must occur within 7 days before randomisation and documented by cardiac ischemic symptoms of ≥ 10 min duration at rest and at least 2 of the following: ST segment changes on electrocardiogram (ECG) indicative of ischemia, or Positive biomarker evdience of myocardial necrosis, or other risk factors such as: 60 yrs of age or older, previous myocardial infarction or coronary bypass surgery, multi-vessel coronary artery disease, diabetes mellitus, peripheral arterial disease, chronic renal disfunction. * Females must be either surgically sterile or post-menopausal. * Activated Clotting Time (ACT) \</= 300 at the time of study treatment Exclusion Criteria: * Participation in another clinical study with an investigational product during the last 30 days. * Current acute complication of percutaneous coronary intervention or coronary bypass surgery. * Any contraindication to ticagrelor, clopidogrel or bivalirudin. * ST elevation myocardial infraction within 24 hours of study entry. * Any indications for oral anticoagulation or aspirin dose other than 75 to 100 milligrams (mg) daily. * Planned use of omeprazole or esomeprazole. * Patients with known bleeding or coagulation disorders; patients requiring dialysis; patients who have an inability to swallow medication. * Patients with known bleeding diathesis or coagulation disorder; history of i…