A Study of Skin and Systemic Biomarkers In Patients With Active Cutaneous Lupus Erythematosus And In Healthy Volunteers

Inclusion Criteria: * Have Discoid Lupus Erythematosus (DLE) or Subacute Cutaneous Lupus Erythematosus (SCLE) with or without a diagnosis of Systemic Lupus Erythematosus (SLE) * Active DLE or active SCLE confirmed by histological analysis (for participants with DLE or SCLE without SLE) * Confirmed diagnosis of SLE using American College of Rheumatology criteria and has current or historical positive antinuclear antibodies (ANA) or anti double-stranded deoxyribonucleic acid (anti-dsDNA) (for participants with DLE or SCLE with SLE) * An active skin lesion that can be biopsied (for participants with lupus erythematosus) Exclusion Criteria: * Known or thought to have a diagnosis of drug-induced lupus * An active skin disease that is not a manifestation of lupus erythematosus * Has an acute cutaneous lupus erythematosus rash only * If taking anti-malarial therapy has not been on a stable dose for at least 8 weeks before Day 1 * Participants treated with greater than 10mg/day of prednisone therapy or equivalent in the last 4 weeks prior to Day 1 * Positive serology for human immunodeficiency virus antibody, hepatitis B virus, or hepatitis C virus