Usefulness of a 2-hour Delta Troponin-I During the ED Identification and Exclusion of Acute Myoca… (NCT02002546) | Clinical Trial Compass
CompletedNot Applicable
Usefulness of a 2-hour Delta Troponin-I During the ED Identification and Exclusion of Acute Myocardial Infarction
United States240 participantsStarted 2014-01
Plain-language summary
1. In chest pain patients with suspected acute coronary syndrome, a 2-hr delta Troponin-I as measured by the i-STAT immunoassay reliably identifies and excludes an acute myocardial infarction.
2. In chest pain patients with suspected acute coronary syndrome whose baseline troponin is above the 99th percentile but less than 0.2ng/ml, a 2hr delta Troponin-I as measured by the i-STAT immunoassay accurately discriminates between acute myocardial infarction and non-acute myocardial infarction troponin elevations.
Who can participate
Age range18 Years
SexALL
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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion criteria
✓. Adult patients 18 years of age or older
✓. Chest pain suspicious for ACS
✓. Absence of ST-segment elevation AMI (STEMI) or STEMI equivalent on the initial ECG
✓. Baseline i-STAT troponin less or equal to 1.0 ng/ml
✓. Enrollment initiated before 2 hour 'delt' troponin value available for review
✓. Ability and willingness to participate and cooperate with telephone follow-up evaluations
Exclusion criteria
✕. ST-elevation or other ECG criteria that results in the diagnosis of AMI and results in patient being sent for percutaneous coronary interventions (PCI) or being treated with thrombolytics
✕. Patients with chest pain not deemed to warrant cardiac screening
✕. Blunt chest trauma
✕. Tachyarrhythmia (ventricular tachycardia, supraventricular tachycardia, or rapid atrial fibrillation)
✕. Cardiac Arrest prior to arrival
✕. Hemodynamically unstable patients
✕. Pulmonary edema requiring CPAP, BIPAP, or mechanical ventilation
✕
What they're measuring
1
Change in Troponin value over a two hour interval.
Timeframe: 2 hours after baseline
Trial details
NCT IDNCT02002546
SponsorChattanooga-Hamilton County Hospital Authority