Tertiary Prevention by Exercise in Colorectal Cancer Therapy (NCT01991847) | Clinical Trial Compass
CompletedNot Applicable
Tertiary Prevention by Exercise in Colorectal Cancer Therapy
Germany50 participantsStarted 2014-01
Plain-language summary
The purpose of this study is to determine the feasibility of a one year exercise training program in post-surgical patients with colorectal cancer.
Who can participate
Age range
40 Years – 80 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* histologically confirmed nonhereditary primary Stage II or III colon cancer diagnosis or rectal cancer
* written informed consent in German
* histopathologically confirmed R0-resection
* start of guideline conformed adjuvant chemotherapy within 12 weeks after R0-resection in Stage III colon cancer diagnosis (if necessary in Stage III colon cancer diagnosis)
Exclusion Criteria:
* hereditary colon cancer diagnosis
* R1 and R2 resection
* clinically relevant complications during recovery
* secondary neoplasm
* non-continuance of guideline conformed therapy
* uncontrolled infection
* manifest cardiac disease (e.g. unstable CAD, heart failure (NYHA IV), malignant hypertension)
* clinical relevant respiratory disease (GOLD IV)
* musculoskeletal disorders severely restricting the patients mobility (e.g. gonarthrosis, coxarthrosis)
* cirrhosis of the liver (Child B and C)
* Karnofsky performance status scale ≤ 60%
* maximal exercise capacity ≤ 50 watt
* clinically relevant lab factors (leukocyte count ≤ 3000/μl, thrombocyte count ≤ 20.000/μl, hemoglobin \< 8 g/dl)
* physical activity level ≥ 18 MET-h/ week at screening
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.