Safety, Tolerability, and Immunogenicity of the Human Cytomegalovirus Vaccine (V160) in Healthy Adults (V160-001)

Inclusion Criteria: * Healthy based on medical history and physical examination * Serologically confirmed to be HCMV seronegative or HCMV seropositive * Agrees to avoid unusual, unaccustomed strenuous, vigorous physical exercise/activity from 72 hours before through 72 hours after each dose of study vaccine * Body weight ≥110 lbs (50 kg) and body mass index (BMI) of 19 to 32 kg/m\^2 * If of reproductive potential, agrees to the following during the study and for 4 weeks after the last dose of study vaccine: 1) practice abstinence from heterosexual activity, or 2) use or have their partner use 2 allowable methods of birth control during heterosexual activity Exclusion Criteria: * Has previously received any cytomegalovirus vaccine * Has history of allergic reaction or anaphylactic reaction to any vaccine component that required medical intervention * Has history of any severe allergic reaction that required medical intervention * Is pregnant or breastfeeding or expecting to conceive from 2 weeks before the study through 1 month after the last dose of study vaccine * Plans to donate eggs or sperm from study start through 1 month after the last dose of study drug * Has impairment of immunologic function including, but not limited to autoimmune disease, splenectomy, or human immunodeficiency virus acquired immunodeficiency syndrome (HIV/AIDS) * Received systemic corticosteroids for ≥14 consecutive days and has not completed treatment within 30 days of study start * Received im…