Expanded Access to B-Domain Deleted Recombinant Porcine Factor VIII (OBI-1) in the Treatment of Acquired Hemophilia A Due to Factor VIII Inhibitory Auto-antibodies

Inclusion Criteria: * Written informed consent from participant or their legal representative. * Participants with acquired hemophilia with autoimmune inhibitors to human factor VIII. * Has a serious bleeding episode, as documented by the investigator. * Be willing and able to follow all instructions and attend all study visits. * Participants taking anti-thrombotics may be included depending on the time elapsed since taking such medications. * Life expectancy of at least 90 days prior to the onset of the bleeding episode. Exclusion Criteria: * Hemodynamically unstable after blood transfusion, fluid resuscitation and pharmacologic or volume replacement pressor therapy. * Has an established reason for bleeding that is not correctable. * Bleeding episode assessed likely to resolve on its own if left untreated. * Anti-OBI-1 inhibitor that exceeds 20 BU (prospectively or retrospectively). * Subsequent bleeding episode at the site of the initial qualifying bleeding episode within 2 weeks following the final OBI-1 dose for the initial qualifying bleeding episode, or subsequent bleeding episode at a different site than the initial qualifying bleeding episode within 1 week following the final OBI-1 dose for the initial qualifying bleeding episode will not be considered "new" qualifying bleeding episodes. * Prior history of bleeding disorder other than acquired hemophilia. * Known major sensitivity (anaphylactoid reactions) to pig or hamster products. * Use of hemophilia medication…