Targeting Circadian and Cognitive Dysfunction in Bipolar Disorder With Modafinil

Inclusion Criteria: * DSM-IV Bipolar Disorder I or Bipolar Disorder II diagnosis * Affectively stable * Clinically acceptable, stably-dosed, mood stabilizing medication regimen for \> 1 month prior to enrollment, with no medication changes planned over the 8-week study period. * Objective evidence of either a subjective sleep quality complaint and/or clinically-significant cognitive impairment at screening. Exclusion Criteria: * History of Central Nervous System trauma, neurological disorder, ADHD, or a learning disability. * Positive urine toxicology or DSM-IV diagnosis of substance abuse/dependence within 3 months * Active, unstable medical problem that may interfere with sleep and/or cognition. * History of substance induced mania * Recent history of rapid cycling * Score of 2 or greater on the decreased need for sleep item on CARS-M * Any drug known to interfere with modafinil * More than 2 psychotropic medications * Abnormal lab or ECG result at screen * Significant suicidal ideation at baseline or at risk for suicidal behavior based on clinical judgment * participation in any other investigational cognitive enhancement study within 6 months