Black Raspberry Confection in Preventing Oral Cancer in Healthy Volunteers

Inclusion Criteria: * Be healthy, free-living adults * Be a non-smoker (defined as adults who have never smoked or who have not had a cigarette in the past ten years) * Agree to consume a standardized vitamin/mineral supplement and avoid other nutrition and alternative supplements for the duration of the study * Agree to follow a berry-restricted diet and to document any accidental consumption of restricted foods each day of the study * Agree to abstain from mouthwashes Exclusion Criteria: * Have an active metabolic or digestive illness including malabsorptive disorders, renal insufficiency, hepatic insufficiency, cachexia, or short bowel syndrome * Have an active or a recent history of any condition that causes altered immunity such as chronic inflammatory disease, autoimmune disorders, cancer, anemia, and blood dyscrasias * Have a known allergy or food intolerance to ingredients in study products (black raspberries),other berries, wheat, or soy * Are strict vegans (no consumption of animal, fish or egg products) * Are planning to conceive, or are currently pregnant or lactating * Are heavy alcohol consumers (defined as an average consumption of greater than 2 drinks/day) * Have a history of oral cancer or currently undergoing treatment of oral cancer * In the last month have had any active oral lesions or maladies or currently have any oral disease or obvious open sores in the oral cavity or surrounding the oral opening * Have strong gag reflex or problems swallowing tha…