A Non-drug Study Profiling Cutaneous Lupus

Inclusion Criteria: * have active DLE or active SCLE confirmed by histological analysis * have a confirmed diagnosis of SLE with SLE Disease Activity Index (SLEDAI) of \>6 and current or historical positive ANA or anti-dsDNA * have an active skin lesion that can be biopsied * if using hydroxychloroquine or chloroquine, must be on stable doses for at least 2 months prior to screening. Exclusion Criteria: * have an active skin disease other than CLE * have any known malignancy within the previous 5 years (with the exception of a non-melanoma skin cancer that has been treated with no evidence of recurrence) * have used a topical corticosteroid on active lesion * have donated blood (volume \>=500 mL) within 56 days prior to screening * has been treated with drugs that are associated with CLE induction within 2 months prior to the screening * have been treated with \>10 mg/day prednisone therapy or equivalent in the last 4 weeks prior to screening.