Efficacy and Safety of Injection With VINCI Plus Hyaluronic Acid Filler

Inclusion Criteria: * Male or female between the ages of 30-65, at the point of screening, wrinkles on both sides of treatment area (nasolabial fold) are in the 3rd or 4th level on the WSRS(Wrinkle Severity Rating Score) * Surrounding soft tissue of wrinkles on both sides of nose and lips are sagging * Wrinkles of both sides of nose and lips are visually symmetric * Agrees to stop all other treatment of facial wrinkle improvement including dermatology treatment during clinical trial * Able to understand and follow instructions and participate the entire period of the clinical trial * Subject voluntarily agrees to participate in clinical trial and gives informed written consent Exclusion Criteria: * At the point of screening, intradermal test results show skin irritation to medical devices of clinical trial * Within 2 weeks before the date of screening, subject has taken antithrombotic (with the exception of low dose aspirin 100mg, up to 300mg/day) or non-steroidal anti-inflammatory medication * Case where subject has abnormal liver function or blood coagulation, has to take antithrombotic medication (with the exception of low dose aspirin 100mg, up to 300mg/day) during clinical trial * Subject has used facial topical liniment (steroids, retinoids: excluding only medicines and cosmetics) within 4 weeks before date of screening or plans to continue using facial topical liniment during clinical trial * Within 6 months before date of screening, subject has received anti-wrinkl…