Tumor and Development (TED)

Inclusion Criteria : \- Patient who developed before the age of 18 years a solid tumour or a malignant or borderline hemopathy. AND * Presenting one or several abnormality (ies) of the development provided it is not related to the treatment and\\or to the disease among: * organ malformation, familial or not * neuro-sensory deficit, familial or not * delay of psychomotor acquisitions * epilepsy (not as a sequelae of the tumour) * disorder of growth and\\or weight and\\or of the cranial perimeter * congenital, sporadic and\\or familial endocrine or metabolic disease * dysmorphy * Informed consent of patient and parents to this study OR * tumour predisposition syndrome or developmental abnormality in a familial context, the molecular basis might have been already identified or not Exclusion Criteria: * absence of malignancy in the index case * lack of developmental anomalies in the index case or in a related first degree * abnormal development recognized as acquired (traumatic, toxic, infectious, perinatal…) * age \> 18 years at diagnosis of the tumor * Lack of informed consent of the legal representatives The familial aggregations of cancer without developmental disease are not included in this study.