A Pilot Study: Treatment of Achilles Tendinopathy With Platelet-Rich Plasma Therapy (NCT01911650) | Clinical Trial Compass
CompletedNot Applicable
A Pilot Study: Treatment of Achilles Tendinopathy With Platelet-Rich Plasma Therapy
United States20 participantsStarted 2013-06
Plain-language summary
The overall goal of this proposal is to correlate ultrasound elastography technique with more standard clinically based outcome measures within the setting of a small sample sized group of patients affected by moderate-to- severe, chronic (\>6months) midsubstance Achilles tendinopathy (AT).
Who can participate
Age range18 Years – 65 Years
SexALL
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Inclusion criteria
✓. age 18-65 years, inclusive
✓. diagnosis of moderate to severe AT, confirmed by Dr. Wilson using clinical symptoms and exam findings consistent with chronic AT (\>6 month duration) - which includes pain while palpating the intratendinous swelling part of the Achilles tendon and relief of pain when tendon placed under tension - and pre-procedure US
✓. self-reported AT-related pain for at least 6 months and VAS (Visual Analog Scale) pain \>5 (0-10 scale)
✓. self-reported failure of eccentric exercise protocol (at least 75% completion)
✓. self-reported failure of at least 2 of the 3 most common treatments for AT (NSAIDS, rest/ice or taping)
✓. patient considered surgery but decided to wait and/or refused surgery -
Exclusion criteria
✕. bilateral AT
✕. insertional AT
✕. local steroid injection within 6 weeks or physical therapy within 4 weeks
✕. inability to comply with follow-up criteria
✕. history of surgery on the Achilles tendon or systemic diseases (general inflammatory diseases such as rheumatologic disorders and diabetes)