A Comparative Efficacy Study: Treatment for Non-healing Diabetic Foot Ulcers

Major Inclusion Criteria: * Subject has a current diagnosis of type I or type II diabetes * Subject's ulcer is on the forefoot or heel * Subject has chronic ulcer - has been present for minimum of 4 weeks * Subject's ulcer extends through the dermis and into the subcutaneous tissue * Subject's HgbA1c \<12% * Subject has adequate circulation to the study foot as evidenced by a Doppler measured ABI greater than or equal to 0.7after 10 minutes rest Major Exclusion Criteria: * Subject has a known sensitivity to bovine- or porcine-derived products. * Subject's ulcer is due to a non-diabetic etiology * Subject's ulcer is over a Charcot deformity of the mid-foot * Subject's random blood sugar readings are \>450 mg/dL * Subject is on dialysis * Subject has a non-study ulcer on the study limb located within 7.0 cm of the study ulcer