Effect of Magnesium on the Recovery Time of Neuromuscular Blockade With Sugammadex (NCT01828385) | Clinical Trial Compass
CompletedPhase 4
Effect of Magnesium on the Recovery Time of Neuromuscular Blockade With Sugammadex
Brazil80 participantsStarted 2012-10
Plain-language summary
The aim of this study is to determine the recovery time of moderate neuromuscular blockade with sugammadex in adults pretreated with magnesium sulfate.
Who can participate
Age range18 Years – 65 Years
SexALL
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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Age 18-65 years
* ASA physical status 1 or 2
* weight BMI 18.5-24.9
* otorhinolaryngological surgeries
Exclusion Criteria:
* major surgery associated with massive blood loss or fluid replacement
* any known allergy to magnesium sulphate or any other study drugs
* pregnant
* anatomical malformations expected to result in a difficult intubation;
* known or suspected neuromuscular disorders and/or significant hepatic or renal dysfunction
* administration of any medication known to interfere with neuromuscular blocking agents (such as anticonvulsants, aminoglycosides, calcium channel blockers and magnesium containing medications)
* hypomagnesemia, hypermagnesemia, hypocalcemia, hypercalcemia
What they're measuring
1
Recovery time of moderate neuromuscular blockade with sugammadex in adults pretreated with magnesium sulfate