Vitamin D as a Supplement Against Falls in Elderly Study (NCT01827345) | Clinical Trial Compass
CompletedNot Applicable
Vitamin D as a Supplement Against Falls in Elderly Study
United States25 participantsStarted 2013-04
Plain-language summary
The role of vitamin D deficiency on increased risk for falls and physical dysfunction is unclear. It is also unclear if taking vitamin D improves physical function and reduces fall risk in older adults. The purpose of this research study is to explore the effects of taking the recommended dose of vitamin D (800 IUs/day) for six months on fall risk and physical functional outcomes in older adults with low vitamin D levels. The investigators hypothesize that the participants will experience fewer falls and function better physically after taking vitamin D for six months.
Who can participate
Age range70 Years
SexALL
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Inclusion Criteria:
* Age ≥ 70 years
* Serum 25-hydroxy vitamin D \>10 ng/mL and \< 30 ng/mL
* Having had a fall at least twice in the past six months
* Provide informed consent
Exclusion Criteria:
* Failure to provide informed consent
* Self-reported myocardial infarction, cerebrovascular accident, or unstable angina within the past 6 months; New York Heart Association (NYHA) Class 3 or 4 congestive heart failure; aortic stenosis; chronic hepatitis; cirrhosis; kidney disease; solid organ transplantation; major psychiatric disorder; history of kidney stones or history of renal colic; history of nephrotic syndrome; history of primary hyperparathyroidism or renal tubular acidosis; history of hypercalcemia; cancer requiring treatment in the past three years, except for non-melanoma skin cancers or cancers that have clearly been cured or in the opinion of the investigator carry an excellent prognosis (e.g., Stage 1 cervical cancer);
* Other significant co-morbid disease (e.g. renal failure on hemodialysis) or severe psychiatric disorder (e.g. bipolar, schizophrenia) that would impair ability to participate in the exercise-based intervention
* Cognitive impairment (i.e., Mini Mental Status Exam score \< 23) or history of significant head injury
* Current use of anabolic medications (i.e., growth hormones or testosterone), antidepressant medications, antipsychotic agents, monoamine oxidase inhibitors, anticholinesterase inhibitors (i.e., Aricept), anticoagulant therapies (aspiri…