Safety and Efficacy of Nonsteroidal Antiinflammatory (NSAI)Drug and Glucocorticoids in Acute Scia… (NCT01816334) | Clinical Trial Compass
CompletedPhase 4
Safety and Efficacy of Nonsteroidal Antiinflammatory (NSAI)Drug and Glucocorticoids in Acute Sciatica
France50 participantsStarted 2013-01
Plain-language summary
The purpose of this study is to determine whether anti-inflammatory drugs or glucocorticoids are effective in the treatment of acute sciatica
Who can participate
Age range18 Years
SexALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* sciatica \<8 weeks resistant to all treatments in ambulatory
* Acute low back pain\> 48 hours;
* Non-deficit patients;
* Initial VAS\> 40/100;
* Consent of patient
* Conflict disco-radicular concordance with the clinical computed tomography scan or magnetic resonance imaging.
* No of contraindications to methylprednisolone, ketoprofen;
* No registration to another protocol;
Exclusion Criteria:
* Pregnant, parturient, lactating mother;
* Diabetic patient;
* Patient with syndrome from narrowing of the lumbar vertebral canal
* Patient with a history of lumbar surgery \<1 year;
* Patient with a Cauda equina syndrome or major motor disability;
* Crural neuralgia
* Patient with a deficit;
* Suspicion of sciatica secondary, ie not conflict-related disco-root: infectious neuritis, fracture on spinal bone tumor ...
associated treatment or pathology contra-indicating administration methylprednisolone, ketoprofen.
What they're measuring
1
Mean visual analogue scale (VAS) for leg pain (radicular pain) in 3 groups