Comparison of Two Strategies of Oropharyngeal and Tracheal Suctioning in Mechanically Ventilated … (NCT01807884) | Clinical Trial Compass
CompletedNot Applicable
Comparison of Two Strategies of Oropharyngeal and Tracheal Suctioning in Mechanically Ventilated Patients
France24 participantsStarted 2014-11-12
Plain-language summary
The purpose of this study is to evaluate the impact of an optimized suctioning procedure on the risk of endotracheal microaspiration, measured by tracheal to oropharyngeal ratio of amylase enzymatic activity.
Who can participate
Age range18 Years
SexALL
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Inclusion Criteria:
* Intubated with a subglottic secretion drainage device
* ventilated more than 48 hours
* patients yielding a significant tracheal suctioning volume (on a semi-qualitative evaluation: ≥ ++ on a scale consisting of 0,+,++,+++)
Exclusion Criteria:
* paralysed patients
* patients with Ramsay 1, 2
* patients breathing spontaneously
* patients less than 18 years old
* patients in a moribund state
* contra-indication for suctioning procedure (risk of haemorrhage, bronchospasm, Acute Respiratory Distress Syndrome with P/F \< 100, malformation or tracheal fistula)
* bronchiectasis, cystic fibrosis, chronic obstructive pulmonary disease
* patients necessitating a closed-suctioning device (prevention of respiratory multiresistant bacteria transmission, Acute Respiratory Distress Syndrome with P/F ratio \< 100)
* pregnant women
What they're measuring
1
tracheal to oropharyngeal ratio of amylase enzymatic activity