Trial Comparing Ablation With Medical Therapy in Patients With Ventricular Tachycardia (NCT01798277) | Clinical Trial Compass
WithdrawnPhase 3
Trial Comparing Ablation With Medical Therapy in Patients With Ventricular Tachycardia
Stopped: Low Enrolment
0Started 2013-04
Plain-language summary
This study aims to compare antiarrhythmic drug therapy with catheter ablation using the SmartTOUCH catheter (Biosense Webster Inc.) as treatment for patients with ventricular tachycardia and coronary artery disease
Who can participate
Age range18 Years – 85 Years
SexALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Sustained monomorphic VT (\>30 seconds, or requiring appropriate ICD therapy in patients with ICDs)
* Documented ischemic heart disease with no further options for revascularization
* Ability and willingness to give written informed consent to participate in the trial
Exclusion Criteria:
* VT in the setting of metabolic abnormalities or acute ischemia if coronary lesions suitable for revascularization are identified.
* Acute ischemia with eligibility for revascularization
* Significant peripheral arterial disease preventing transvascular access to the left ventricle.
* Patients with arrhythmogenic right ventricular cardiomyopathy (ARVC), hypertrophic cardiomyopathy, Brugada syndrome, Long QT syndromes, dilated cardiomyopathy
* Prior long term therapy with a Class III or Class IC antiarrhythmic agent (longer than 2 weeks)
* Patient is or may be potentially pregnant
* Patient has a mechanical heart valve
* Myocardial infarction within the past 90 days
* Stroke within the past 90 days
* New York Heart Association (NYHA) functional class IV
* Hemorrhagic manifestations, bleeding diathesis, or impairment of hemostasis
* Lesions at risk of clinically significant bleeding (e.g., extensive cerebral infarction within the last 6 months, active peptic ulcer disease with recent bleeding)
* Prior VT ablation procedure
* Contraindication or allergy to contrast media, routine procedural medications or catheter materials
* Contraindications to an interventional proce…
What they're measuring
1
Recurrence of Ventricular Tachycardia
Timeframe: 1 year
Trial details
NCT IDNCT01798277
SponsorNewmarket Electrophysiology Research Group Inc